SIM2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A15098-20, A15098-100
Citations, Manuals and MSDS Available upon request.
Background: This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 73kDa
Observed Molecular Weight: 73kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 6493
SWISS: Q14190
Alternate Names: SIM; bHLHe15; HMC13F06; HMC29C01; SIM2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Cancer, Tumor biomarkers, Neuroscience.
NCBI Alias: SIM2
Research Use Only