SLC7A11/xCT Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A13685-20, A13685-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc (-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 55 kDa
Observed Molecular Weight: 55 kDa/35 kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 23657
SWISS: Q9UPY5
Alternate Names: xCT; CCBR1; SLC7A11/xCT
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:5000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Endocrine Metabolism, Amino acid metabolism.
NCBI Alias: SLC7A11
Research Use Only