Smac/Diablo Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2564-20, A2564-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes an inhibitor of apoptosis protein (IAP) -binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IP, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 27kDa
Observed Molecular Weight: 18kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 56616
SWISS: Q9NR28
Alternate Names: SMAC; DFNA64; Smac/Diablo
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Invasion and Metastasis, Cell Biology Developmental Biology, Apoptosis, Mitochondrial Control of Apoptosis, Inhibition of Apoptosis, Death Receptor Signaling Pathway, Endocrine Metabolism, Mitochondrial metabolism, Mitochondrial markers.
NCBI Alias: DIABLO
Research Use Only