SNW1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A14580-20, A14580-100
Citations, Manuals and MSDS Available upon request.
Background: This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly (A) -binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 61kDa
Observed Molecular Weight: 70kDa/75kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 22938
SWISS: Q13573
Alternate Names: Bx42; SKIP; FUN20; Prp45; SKIIP; SKIP1; PRPF45; NCOA-62; SNW1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:100 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling, Cell Biology Developmental Biology.
NCBI Alias: SNW1
Research Use Only