SOST Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A24852-20, A24852-100
Citations, Manuals and MSDS Available upon request.
Background: Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 24kDa
Observed Molecular Weight: 27kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 50964
SWISS: Q9BQB4
Alternate Names: SOST; CDD; DAND6; SOST1; VBCH; sclerostin
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Stem Cells.
NCBI Alias: SOST
Research Use Only