SP100 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5851-20, A5851-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia) -SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 100kDa
Observed Molecular Weight: 66-100kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 6672
SWISS: P23497
Alternate Names: lysp100b; SP100
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Immunology Inflammation.
NCBI Alias: SP100
Research Use Only