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Staufen Rabbit pAb - A4131

Staufen Rabbit pAb - A4131

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Staufen Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A4131-20, A4131-100

Citations, Manuals and MSDS Available upon request.

Background: Staufen is a member of the family of double-stranded RNA (dsRNA) -binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 63kDa

Observed Molecular Weight: 63kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 6780

SWISS: O95793

Alternate Names: STAU; PPP1R150; Staufen

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Microtubules, Neuroscience.

NCBI Alias: STAU1

Research Use Only