TDO2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A13182-20, A13182-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 48kDa
Observed Molecular Weight: 48kDa/
Immunogen: Synthetic peptide
Species: Human
GeneID: 6999
SWISS: P48775
Alternate Names: TO; TDO; TPH2; TRPO; HYPTRP; TDO2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Amino acid metabolism.
NCBI Alias: TDO2
Research Use Only