TEK Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A7222-20, A7222-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF) -like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 126kDa
Observed Molecular Weight: 126kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 7010
SWISS: Q02763
Alternate Names: TIE2; VMCM; GLC3E; TIE-2; VMCM1; CD202B; TEK
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Kinase, Tyrosine kinases, Cell Biology Developmental Biology, Growth factors, Immunology Inflammation, CDs, Stem Cells, Cardiovascular, Angiogenesis.
NCBI Alias: TEK
Research Use Only