THPO Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1825-20, A1825-100
Citations, Manuals and MSDS Available upon request.
Background: Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 38kDa
Observed Molecular Weight: 38kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 7066
SWISS: P40225
Alternate Names: ML; TPO; MGDF; MKCSF; MPLLG; THCYT1; THPO
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Cell Biology Developmental Biology, Cell Cycle, Cell differentiation, Growth factors, Immunology Inflammation, Cytokines, Stem Cells, Mesenchymal Stem Cells, Cardiovascular, Blood.
NCBI Alias: THPO
Research Use Only