TIGAR Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A20416-20, A20416-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2, 6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 30kDa
Observed Molecular Weight: 30kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 57103
SWISS: Q9NQ88
Alternate Names: FR2BP; C12orf5; TIGAR
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Tumor suppressors, p53 pathway, Cell Biology Developmental Biology, Apoptosis, Endocrine Metabolism, Warburg Effect.
NCBI Alias: TIGAR
Research Use Only