TIMP3 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A11986-20, A11986-100
Citations, Manuals and MSDS Available upon request.
Background: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 24kDa
Observed Molecular Weight: 20kDa/25kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 7078
SWISS: P35625
Alternate Names: SFD; K222; K222TA2; HSMRK222; TIMP3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Invasion and Metastasis, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Cytoskeleton, Extracellular Matrix, Ubiquitin, Neuroscience, Cardiovascular, Angiogenesis.
NCBI Alias: TIMP3
Research Use Only