TJP2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0594-20, A0594-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
Category: Polyclonal Antibodies
Applications: WB, IP, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 134kDa
Observed Molecular Weight: 160kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 9414
SWISS: Q9UDY2
Alternate Names: ZO2; X104; FHCA1; PFIC4; DFNA51; DUP9q21.11; C9DUPq21.11; TJP2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Tight Junctions, Cytoskeleton.
NCBI Alias: TJP2
Research Use Only