TLN1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A4158-20, A4158-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.
Category: Polyclonal Antibodies
Applications: WB, IF-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 270kDa
Observed Molecular Weight: 240kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 7094
SWISS: Q9Y490
Alternate Names: TLN; ILWEQ; talin-1; TLN1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Cytoskeleton, Microfilaments, Immunology Inflammation, T Cell Receptor Signaling Pathway.
NCBI Alias: TLN1
Research Use Only