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TNFRSF10A Rabbit pAb - A6267

TNFRSF10A Rabbit pAb - A6267

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TNFRSF10A Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A6267-20, A6267-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human

Protein Weight: 50kDa

Observed Molecular Weight: 45kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 8797

SWISS: O00220

Alternate Names: DR4; APO2; CD261; TRAILR1; TRAILR-1; TNFRSF10A

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cell Biology Developmental Biology, Apoptosis, Death Receptor Signaling Pathway, Immunology Inflammation, CDs, Cytokines, NF-kB Signaling Pathway, Cell Intrinsic Innate Immunity Signaling Pathway.

NCBI Alias: TNFRSF10A

Research Use Only