TNNC1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1927-20, A1927-100
Citations, Manuals and MSDS Available upon request.
Background: Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.
Category: Polyclonal Antibodies
Applications: WB, IF-P, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 18kDa
Observed Molecular Weight: 18kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 7134
SWISS: P63316
Alternate Names: TNC; TN-C; TNNC; CMD1Z; CMH13; TNNC1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:5000 IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Microfilaments, Cardiovascular, Heart, Contractility.
NCBI Alias: TNNC1
Research Use Only