TSG101/VPS23 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2216-20, A2216-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 44kDa
Observed Molecular Weight: 44kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 7251
SWISS: Q99816
Alternate Names: TSG10; VPS23; TSG101/VPS23
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50-1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Cancer, Cell Biology Developmental Biology, Cell Cycle, Cell cycle inhibitors, Cell differentiation.
NCBI Alias: TSG101
Research Use Only