WHSC1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A7938-20, A7938-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t (4;14) (p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 152kDa
Observed Molecular Weight: 80kDa, 152kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 7468
SWISS: O96028
Alternate Names: WHS; TRX5; KMT3F; KMT3G; MMSET; RAUST; WHSC1; REIIBP
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Epigenetic writers and erasers of core Histones, Transcription Factors.
NCBI Alias: NSD2
Research Use Only