XCR1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A20258-20, A20258-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains. The encoded protein transduces a signal by increasing the intracellular calcium ion level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Some studies have implicated a cluster of genes at 3p21.31, including this gene, as associated with COVID-19 risk. The encoded protein may also play a role in cell proliferation and migration in several types of cancer.
Category: Polyclonal Antibodies
Applications: IHC-P, ELISA
Cross-reactivity: Rat
Protein Weight: 39kDa
Observed Molecular Weight: Refer to figures
Immunogen: Synthetic peptide .
Species: Human
GeneID: 2829
SWISS: P46094
Alternate Names: GPR5; CCXCR1; XCR1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, Immunology Inflammation, Cell Intrinsic Innate Immunity Signaling Pathway.
NCBI Alias: XCR1
Research Use Only