XPD/ERCC2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5640-20, A5640-100
Citations, Manuals and MSDS Available upon request.
Background: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Rat
Protein Weight: 87kDa
Observed Molecular Weight: 87kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 2068
SWISS: P18074
Alternate Names: EM9; TTD; XPD; TTD1; COFS2; TFIIH; XPD/ERCC2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair, Cell Biology Developmental Biology, Apoptosis.
NCBI Alias: ERCC2
Research Use Only