ZAK Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A14513-20, A14513-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 35kDa/51kDa/91kDa
Observed Molecular Weight: 105kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 51776
Alternate Names: pk; AZK; MLT; MRK; ZAK; CNM6; MLK7; MLTK; SFMMP; mlklak; MLTKbeta; MLTKalpha
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Signal Transduction, Kinase, MAPK-JNK Signaling Pathway, Cell Biology Developmental Biology, Apoptosis.
NCBI Alias: MAP3K20
Research Use Only