Acetyl-Histone H3-K18 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A7257-20, A7257-100
Citations, Manuals and MSDS Available upon request.
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.
Category: Acetylated Antibodies
Applications: WB, DB, IHC-P, IF/ICC, ELISA, ChIP
Cross-reactivity: Human, Mouse, Rat, Other (Wide Range Predicted)
Protein Weight: 15kDa
Observed Molecular Weight: 17kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 8290/8350
SWISS: Q16695/P68431
Alternate Names: H3/j; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3FJ; H3C10; H3C11; HIST1H3J; Acetyl-Histone H3-K18
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 DB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. ChIP, 5μg antibody for 5μg-10μg of Chromatin
Research Areas: Epigenetics & Nuclear Signaling, Epigenetic Modifications, Acetylation, Epigenetics & Nuclear Signaling, Epigenetic Modifications, Acetylation, Epigenetics & Nuclear Signaling, Epigenetic Modifications, Acetylation.
NCBI Alias: H3C12
Research Use Only