14-3-3 Epsilon Polyclonal Antibody
Sizes: 20μL, 50μL, 100μL
Catalogue Numbers: BT-AP00007-20, BT-AP00007-50, BT-AP00007-100
Citations, Manuals and MSDS Available upon request.
Background: YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma) product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
Research Areas: Neuroscience; Signal Transduction
Target Protein: YWHAE
Applications: WB, IHC-p
Reactivity: Mouse, Rat
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
Full Product Name: 14-3-3 epsilon Antibody
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Storage: -20°C for 1 year
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Molecular Weight (Da): 28303
UniProt Accession: Human: P61981; Mouse: P61982; Rat: P61983
Synonyms: YWHAE; 14-3-3 protein epsilon; 14-3-3E
GeneID: Human: 7532; Mouse: 22628; Rat: 56010
Research Use Only