17β-HSD4 rabbit pAb
Sizes: 50μL, 100μL
Catalogue Numbers: ES4116-50, ES4116-100
Citations, Manuals and MSDS Available upon request.
Background: hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4) Homo sapiens The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
Alternate Name: HSD17B4; EDH17B4; Peroxisomal multifunctional enzyme type 2; MFE-2; 17-beta-hydroxysteroid dehydrogenase 4; 17-beta-HSD 4; D-bifunctional protein; DBP; Multifunctional protein 2; MPF-2
Source: Rabbit
Applications: WB; IHC; IF; ELISA
Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Reactivity: Human; Mouse; Rat
Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human HSD17B4. AA range:41-90
Storage and Stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band (KD): 80kD
Human Gene ID: 3295
Human SWISS Prot NO: P51659
Subcellular Location: Peroxisome.
Research Use Only