2AAA Polyclonal Antibody
Sizes: 20μL, 50μL, 100μL
Catalogue Numbers: BT-AP08343-20, BT-AP08343-50, BT-AP08343-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases| and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme| which is composed of a catalytic subunit and a constant regulatory subunit| that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.
Research Areas: Signal transduction; Cell biology
Target Protein: PPP2R1A
Applications: WB, ELISA
Reactivity: Human, Mouse
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
Full Product Name: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Storage: -20°C for 1 year
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
UniProt Accession: Human: P30153; Mouse: Q76MZ3
Synonyms: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform;Medium tumor antigen-associated 61 kDa protein;PP2A subunit A isoform PR65-alpha;PP2A subunit A isoform R1-alpha
GeneID: Human: 5518
Research Use Only