AAK1 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA21530-50, RA21530-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification Technology:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Names: AAK1; KIAA1048; AP2-associated protein kinase 1; Adaptor-associated kinase 1
Background: AP2 associated kinase 1(AAK1) Homo sapiens Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],
Applications: WB, IHC-p, IF/ICC, ELISA
Species Cross-Reactivity: Human, Mouse, Rat, Monkey
Molecular Weight: 94
Protein Molecular Weight (kDa): 94
GeneID (Human): 22848
SWISS: Q2M2I8
Source: Rabbit
Immunogen: The antiserum was produced against synthesized peptide derived from human AAK1. AA range:271-320
Category: Polyclonal
Research Use Only