AANAT Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A11850-20, A11850-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: DSPS; SNAT; AANAT
GeneID: 15
Swiss Prot: Q16613
Tested Applications: ELISA, WB
Reactivity: Human
Calculated Molecular Weight: 23kDa
Observed Molecular Weight: 35kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human AANAT (NP_001079.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Epigenetics Nuclear Signaling, Cancer, Endocrine Metabolism, Neuroscience
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: 293T
Cellular Location: Cytoplasm
Keywords: 15, sc-55612, sc-68346, AANAT, DSPS, SNAT, aralkylamine N-acetyltransferase, serotonin N-acetyltransferase, arylalkylamine N-acetyltransferase, serotonin acetylase, Q16613, Aralkylamine N-Acetyltransferase, Arylalkylamine N-Acetyltransferase, Serotonin N-Acetyltransferase, Serotonin Acetylase, EC 2.3.1.87, AA-NAT, sc55612, sc 55612, sc68346, sc 68346, AA NAT, Serotonin acetylase, Serotonin N acetyltransferase
Symbol: AANAT
Category: Polyclonal Antibodies
Research Use Only