ABCBB Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA30948-50, RA30948-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Store At/In: -20°C/1 year
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Background: ATP binding cassette subfamily B member 11 (ABCB11) Homo sapiens The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008],
Applications: WB; ELISA
Species Cross-Reactivity: Human; Rat; Mouse;
Molecular Weight: 145
GeneID (Human): 8647
Protein MW (KDa): 145
SWISS: O95342
Source: Rabbit
Research Use Only