ABflo® 700 Rat anti-Mouse CD3 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A27432-100, A27432-200, A27432-500
Citations, Manuals and MSDS Available upon request.
Background: Predicted to enable identical protein binding activity and transmembrane signaling receptor activity. Involved in positive thymic T cell selection. Part of alpha-beta T cell receptor complex. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in immunodeficiency 19 and severe combined immunodeficiency. Orthologous to human CD3D (CD3d molecule). Predicted to enable several functions, including SH3 domain binding activity; identical protein binding activity; and protein heterodimerization activity. Involved in nervous system development and positive regulation of cell adhesion. Acts upstream of or within several processes, including positive regulation of T cell activation; positive regulation of cytokine production; and regulation of signal transduction. Located in several cellular components, including dendritic spine; external side of plasma membrane; and immunological synapse. Part of alpha-beta T cell receptor complex. Is expressed in colon and hemolymphoid system. Human ortholog(s) of this gene implicated in immunodeficiency 18. Orthologous to human CD3E (CD3e molecule).
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Mouse
Protein Weight: 19kDa/21kDa Immunogen: Synthetic peptide.
Species: Mouse
GeneID: 12500/12501
SWISS: P04235/P22646
Alternate Names: T3d; CD3; T3e; CD3epsilon
Source: Rat
Isotype: IgG2b, κ
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Immunology Adaptive Immunity T Cells CDStem Cells Hematopoietic Progenitors Hematopoietic Stem Cells Human Lineage NegativeImmunology Adaptive Immunity Regulatory T Cells
NCBI Alias: CD3E/CD3D
Modifications: Unmodified
Conjugate: ABflo® 700. Ex:690nm. Em:713nm.
Clone Number Info: ATC0031
Research Use Only