ACACB Rabbit Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA21572-50, RA21572-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store At/In: -20°C/1 year
Recommended Dilutions: WB 1:500-2000
Background: acetyl-CoA carboxylase beta (ACACB) Homo sapiens Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008],
Applications: WB
Species Cross-Reactivity: Human; Rat; Mouse;
GeneID (Human): 32
SWISS: O00763
Source: Rabbit
Research Use Only