ACCα (phospho Ser80) Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA21584-50, RA21584-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store At/In: -20°C/1 year
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Alternative Names: ACACA; ACAC; ACC1; ACCA; Acetyl-CoA carboxylase 1; ACC1; ACC-alpha
Background: acetyl-CoA carboxylase alpha (ACACA) Homo sapiens Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Applications: WB; IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
Molecular Weight: 280
GeneID (Human): 31
Protein MW (KDa): 280
SWISS: Q13085
Source: Rabbit
Research Use Only