ACE1 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA21586-50, RA21586-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store At/In: -20°C/1 year
Recommended Dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Alternative Names: Angiotensin-converting enzyme (ACE; EC 3. 2. 1. -; EC 3. 4. 15. 1; Dipeptidyl carboxypeptidase I; Kininase II; CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]
Background: angiotensin I converting enzyme (ACE) Homo sapiens This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010],
Applications: IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 1636
SWISS: P12821
Source: Rabbit
Research Use Only