ACE2 Rabbit Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA21589-50, RA21589-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.06% sodium azide.
Store At/In: -20°C/1 year
Recommended Dilutions: IHC-p1:50-200 ,WB 1:1000-2000
Alternative Names: Angiotensin-converting enzyme 2 (EC 3. 4. 17. 23) (ACE-related carboxypeptidase) (Angiotensin-converting enzyme homolog) (ACEH) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2]; YM33046
Background: angiotensin I converting enzyme 2 (ACE2) Homo sapiens The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Applications: IHC-p; WB
Species Cross-Reactivity: Human; Mouse; Rat
Molecular Weight: 120-135
GeneID (Human): 59272
Protein MW (KDa): 120-135
SWISS: Q9BYF1
Source: Rabbit
Research Use Only