AChRα3 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA21603-50, RA21603-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store At/In: -20°C/1 year
Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Alternative Names: CHRNA3; NACHRA3; Neuronal acetylcholine receptor subunit alpha-3
Background: cholinergic receptor nicotinic alpha 3 subunit (CHRNA3) Homo sapiens This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009],
Applications: WB; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
Molecular Weight: 57
GeneID (Human): 1136
Protein MW (KDa): 57
SWISS: P32297
Source: Rabbit
Research Use Only