Ack1 Rabbit pAb
Sizes: 50µl, 100µl
Catalogue Numbers: RA36736-50, RA36736-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, and 0.44% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: WB 1:500-2000
Purification Technology:The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Alternative Names: Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)
Background: tyrosine kinase non receptor 2(TNK2) Homo sapiens This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008],
Applications: WB
Species Cross-Reactivity: Human, Mouse, Rat
GeneID (Human): 10188
SWISS: Q07912
Source: Rabbit
Immunogen: Synthesized peptide derived from human Ack1
Category: Polyclonal
Research Use Only