ACL6B Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA30981-50, RA30981-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Store At/In: -20°C/1 year
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Background: actin like 6B (ACTL6B) Homo sapiens The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants. [provid
Applications: WB; ELISA
Species Cross-Reactivity: Human; Mouse
Molecular Weight: 46
GeneID (Human): 51412
Protein MW (KDa): 46
SWISS: O94805
Source: Rabbit
Research Use Only