ACTC1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A6507-20, A6507-100
Citations, Manuals and SDS Available upon request.
Background: Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).
Synonyms: ACTC; ASD5; CMD1R; CMH11; LVNC4; ACTC1
GeneID: 70
Swiss-Prot: P68032
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 42kDa
Observed Molecular Weight: 42kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ACTC1 (NP_005150.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cytoskeleton, Microfilaments, Actins, Cardiovascular, Heart, Contractility
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: C2C12, H9C2, RD, Mouse lung, Mouse heart, Rat lung, Rat heart
Cellular Location: Cytoplasm, Cytoskeleton
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.