AF/LE Purified Anti-Human/Mouse IL-5 Antibody [TRFK5] - E-AB-F12050

AF/LE Purified Anti-Human/Mouse IL-5 Antibody [TRFK5]

Sizes: 500μg, 1mg

Catalogue Numbers: E-AB-F12050-500, E-AB-F12050-1

Citations, Manuals and MSDS Available upon request.

Abbreviation: IL-5

Target Synonym: Interleukin-5, IL-5, B-cell differentiation factor I, T-cell replacing factor, TRF,

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Host: Rat

Species Reactivity: Human, Mouse

Application: ICFCM, Depletion, Neut

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Rat IgG1, κ

Clone No.: TRFK5

UNIProt ID: P05113, P04401,

Background: IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F098230

Buffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Gene ID: 356, 716, 191

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag

Research Use Only