AF/LE Purified Anti-Mouse CD119 Antibody [GR-20] - E-AB-F11150

AF/LE Purified Anti-Mouse CD119 Antibody [GR-20]

Sizes: 500μg, 1mg

Catalogue Numbers: E-AB-F11150-500, E-AB-F11150-1

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD119

Target Synonym: Interferon gamma receptor 1, Ifngr1, IFN-gamma-R1, IFN-gamma-R-alpha, CD119,

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Host: Rat

Species Reactivity: Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Rat IgG2a, κ

Clone No.: GR-20

UNIProt ID: P15261

Background: CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F098330

Buffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Gene ID: 15979

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag

Research Use Only