AKR1A1 Polyclonal Antibody
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Catalogue Numbers: BS5603-50, BS5603-100
Sizes: 50µl, 100µl
Swiss-Prot: P14550
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC
Background: AKR1A1 (aldo-keto reductase family 1 member A1), also known as ALR (aldehyde reductase), DD3 (dihydrodiol dehydrogenase 3) or ALDR1 (alcohol dehydrogenase), is a widely and abundantly expressed member of the aldo-keto reductase (AKR) family of proteins. Members of the AKR family are soluble NADPH-dependent oxidoreductases. They play important roles in the metabolism of drugs, carcinogens and reactive aldehydes. AKR1A1 exists as a monomer and catalyzes the reduction of xenobiotic and biogenic aldehydes and ketones to their corresponding alcohols.
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Specificity: AKR1A1 polyclonal antibody detects endogenous levels of AKR1A1 protein.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of AKR1A1 polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: Raw264.7 cell lysate
Lane 3: H9C2 cell lysate, Immunohistochemistry (IHC) analyzes of AKR1A1 pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50,showing cytoplasmic and nuclear staining.Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.
Bioworld Molecular Weight: ~ 37 kDa
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Alternative Name: Alcohol dehydrogenase [NADp (+)]; Aldehyde reductase; Aldo-keto reductase family 1 member A1; AKR1A1; ALDR1; ALR
Immunogen: A synthetic peptide corresponding to residues in Human AKR1A1.
Conjugate: Unconjugated
Modification: Unmodified