AKR1B1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A1684-20, A1684-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.
Synonyms: AR; ADR; ALR2; ALDR1; AKR1B1
GeneID: 231
Swiss-Prot: P15121
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IF/ICC
Calculated Molecular Weight: 36kDa
Observed Molecular Weight: 36kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-316 of human AKR1B1 (NP_001619.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism
Recommended Dilutions: WB: 1:500 - 1:1000 | IF/ICC: 1:50 - 1:200
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm
Positive Samples: U-251MG, 293T, Raji, Mouse kidney, Rat testis, Rat skeletal muscle, Rat kidney
Keywords: 231, sc-17736, sc-17735, sc-17732, sc-17733, sc-33219, AKR1B1, ADR, ALDR1, ALR2, AR, aldo-keto reductase family 1 member B, aldose reductase, Lii5-2 CTCL tumor antigen, aldehyde reductase 1, aldo-keto reductase family 1 member B1, low Km aldose reductase, P15121, Aldo-Keto Reductase Family 1 Member B, Aldo-Keto Reductase Family 1 Member B1, Aldose Reductase, Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase), Lii5-2 CTCL Tumor Antigen, Low Km Aldose Reductase, Aldehyde Reductase 1, Aldehyde Reductase, EC 1.1.1.21, MGC1804, sc17736, sc 17736, sc17735, sc 17735, sc17732, sc 17732, sc17733, sc 17733, sc33219, sc 33219, Aldehyde reductase, Aldose reductase
Symbol: AKR1B1
Category: Polyclonal Antibodies
Research Use Only