AKR1C2 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A1048-20, A1048-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
Synonyms: DD; DD2; TDD; BABP; DD-2; DDH2; HBAB; HAKRD; MCDR2; SRXY8; DD/BABP; AKR1C-pseudo; AKR1C2
GeneID: 1646
Swiss Prot: P52895
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 37kDa
Observed Molecular Weight: 37kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human AKR1C2 (NP_995317.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:1000 - 1:5000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:100
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Mouse kidney, Rat kidney
Cellular Location: Cytoplasm
Keywords: 1646, AKR1C2, AKR1C-pseudo, BABP, DD, DD-2, DD/BABP, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8, TDD, aldo-keto reductase family 1 member C2, 3-alpha-HSD3, chlordecone reductase homolog HAKRD, dihydrodiol dehydrogenase 2, bile acid binding protein, 3-alpha hydroxysteroid dehydrogenase, type III, pseudo-chlordecone reductase, testicular 17, 20-desmolase deficiency, trans-1, 2-dihydrobenzene-1, 2-diol dehydrogenase, type II dihydrodiol dehydrogenase, P52895, Aldo-Keto Reductase Family 1 Member C2, Dihydrodiol Dehydrogenase 2, Bile Acid Binding Protein, 3-Alpha Hydroxysteroid Dehydrogenase, Type III, Trans-1, 2-Dihydrobenzene-1, 2-Diol Dehydrogenase, Testicular 17, 20-Desmolase Deficiency, Chlordecone Reductase Homolog HAKRD, 3-Alpha-HSD3, Aldo-Keto Reductase Family 1, Member C2 (Dihydrodiol Dehydrogenase 2, Type III), Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein, Type III 3-Alpha-Hydroxysteroid Dehydrogenase, Type II Dihydrodiol Dehydrogenase, Pseudo-Chlordecone Reductase, AKR1C-Pseudo, EC 1.1.1.357, EC 1.3.1.20, EC 1.-.-.-, AKR1Cpseudo, AKR1C pseudo, DD 2
Symbol: AKR1C2
Category: Polyclonal Antibodies
Research Use Only