AKR1C3 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A3884-20, A3884-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene.
Synonyms: DD3; DDX; PGFS; HAKRB; HAKRe; HA1753; HSD17B5; hluPGFS; AKR1C3
GeneID: 8644
Swiss-Prot: P42330
Reactivity: Human, Mouse
Calculated Molecular Weight: 37kDa
Observed Molecular Weight: 37kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human AKR1C3 (P42330).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IF/ICC: 1:50 - 1:200
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Growth factors, Endocrine Metabolism, Neuroscience
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HepG2, Mouse liver
Cellular Location: Cytoplasm
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.