ANPRB/NRP2 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A19255-20, A19255-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.
Synonyms: GCB; AMD1; AMDM; ANPb; ECDM; GC-B; NPRB; SNSK; ANPRB; GUC2B; NPRBi; GUCY2B; ANPRB/NRP2
GeneID: 4882
Swiss-Prot: P20594
Reactivity: Mouse
Tested Applications: ELISA, WB
Calculated Molecular Weight: 117kDa
Observed Molecular Weight: 130kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 800-900 of human ANPRB/NRP2 (P20594).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors (GPCR), Neuroscience, Cardiovascular, Blood
Recommended Dilutions: WB: 1:500 - 1:1000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Membrane, Single-pass Type I Membrane Protein
Positive Samples: Mouse lung, Mouse spleen
Keywords: AMDM, ANP B, ANPR B, ANPRB, GC B, Guanylate cyclase B, GUC2B, GUCY2B, Natriuretic Peptide Receptor B, NPR2, NPRB, ANPb, ECDM, NPRBi, SNSK, natriuretic peptide receptor 2, atrial natriuretic peptide receptor 2, ANP-B, ANPR-B, GC-B, NPR-B, atrial natriuretic peptide B-type receptor, atrial natriuretic peptide receptor type B, guanylate cyclase 2B, guanylate cyclase B, natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B), P20594, 4882, CI 13kD A, Complex I 13kD A, NDUFS6, Unconjugated, ANPRB/NRP2
Symbol: NPR2
Category: Monoclonal Antibodies
Research Use Only