APOA1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A14211-20, A14211-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein.
Synonyms: HPALP2; apo(a); APOA1
GeneID: 335
Swiss-Prot: P02647
Reactivity: Mouse, Rat
Tested Applications: ELISA, WB, IHC-P
Calculated Molecular Weight: 28kDa
Observed Molecular Weight: 31kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-267 of human APOA1 (NP_000030.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Lipid Metabolism, Neuroscience, Neurodegenerative Diseases, Cardiovascular, Heart, Lipids, Cardiovascular diseases, Heart disease
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Secreted
Positive Samples: Mouse lung, mouse liver, mouse small intestine, rat lung, rat liver
Keywords: 335, sc-19029, sc-23605, sc-30089, Apo AI, ApoA I, APOA1, apolipoprotein A I, Apolipoprotein A1, apo(a), apolipoprotein A1, apolipoprotein A-I, apo-AI, P02647, Apolipoprotein A-I, Apo-AI, Apo(A), ApoA-I
Symbol: APOA1
Category: Polyclonal Antibodies
Research Use Only