ARHGEF7 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A1108-20, A1108-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
Synonyms: P50; P85; PAK3; PIXB; COOL1; P50BP; COOL-1; P85SPR; BETA-PIX; P85COOL1; Nbla10314; ARHGEF7
GeneID: 8874
Swiss Prot: Q14155
Tested Applications: ELISA, WB
Reactivity: Human, Mouse
Calculated Molecular Weight: 90kDa
Observed Molecular Weight: 86kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ARHGEF7 (NP_001106984.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Cancer, Signal Transduction, G protein signaling, Small G proteins, Cell Biology Developmental Biology, Cytoskeleton, Microfilaments, Microtubules, Actins
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: SW620, Jurkat, COS-1, COS-7, MCF7, K-562, Mouse lung, Mouse heart
Cellular Location: Cell Junction, Cell Projection, Cytoplasm, Cell Cortex, Focal Adhesion, lamellipodium, ruffle,
Keywords: 8874, sc-10932, sc-10931, sc-25418, ARHGEF7, BETA-PIX, COOL-1, COOL1, Nbla10314, P50, P50BP, P85, P85COOL1, P85SPR, PAK3, PIXB, Rho guanine nucleotide exchange factor 7, rho guanine nucleotide exchange factor 7, PAK-interacting exchange factor beta, Rho guanine nucleotide exchange factor (GEF) 7, SH3 domain-containing proline-rich protein, Q14155, Rho Guanine Nucleotide Exchange Factor 7, PAK-Interacting Exchange Factor Beta, Rho Guanine Nucleotide Exchange Factor (GEF) 7, SH3 Domain-Containing Proline-Rich Protein, Beta-Pix, KIAA0142, PAK3BP, BETAPIX, BETA PIX, DKFZp686C12170, DKFZp761K1021, KIAA0412, COOL 1, sc10932, sc 10932, sc10931, sc 10931, sc25418, sc 25418
Symbol: ARHGEF7
Category: Polyclonal Antibodies
Research Use Only