ARRB2 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A1171-20, A1171-100
Citations, Manuals and SDS Available upon request.
Background: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: ARB2; ARR2; BARR2; ARRB2
GeneID: 409
Swiss Prot: P32121
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 46kDa
Observed Molecular Weight: 46kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300-400 of human ARRB2 (NP_004304.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, Cell Biology Developmental Biology
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa
Cellular Location: Cell Membrane, Cytoplasm, Cytoplasmic Vesicle, Membrane, Nucleus, Clathrin-coated Pit,
Keywords: 409, sc-6386, sc-6387, sc-30938, sc-30936, sc-98833, ARB2, ARR2, ARRB2, Arrestin beta 2, arrestin, beta 2, BARR2, Beta arrestin 2, arrestin beta 2, beta-arrestin-2, arrestin 3, P32121, Arrestin Beta 2, Non-Visual Arrestin-3, Arrestin 3, Arrestin, Beta 2, Beta-Arrestin-2, Arrestin Beta-2, DKFZp686L0365, Beta Arrestin 2, sc6386, sc 6386, sc6387, sc 6387, sc30938, sc 30938, sc30936, sc 30936, sc98833, sc 98833
Symbol: ARRB2
Category: Polyclonal Antibodies
Research Use Only