ATG7 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A21895-20, A21895-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants.
Synonyms: GSA7; APG7L; SCAR31; APG7-LIKE; ATG7
GeneID: 10533
Swiss-Prot: O95352
Reactivity: Human
Tested Applications: ELISA, WB, IHC-P, IP
Calculated Molecular Weight: 78kDa
Observed Molecular Weight: 75kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 600-703 of human ATG7 (O95352).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Autophagy, Ubiquitin, Endocrine Metabolism, Mitochondrial metabolism, Immunology Inflammation, Cardiovascular, Heart
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200 | IP: 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm, Preautophagosomal Structure
Positive Samples: HepG2
Keywords: sc-8668, sc-12497, sc-33211, APG7 LIKE, APG7L, ATG7, Autophagy related protein 7, GSA7, hAGP7, APG7-LIKE, autophagy related 7, ubiquitin-like modifier-activating enzyme ATG7, APG7 autophagy 7-like, ATG12-activating enzyme E1 ATG7, ubiquitin-activating enzyme E1-like protein, O95352, 10533, APG7LIKE, DKFZp434N0735, sc8668, sc 8668, sc12497, sc 12497, sc33211, sc 33211
Symbol: ATG7
Category: Monoclonal Antibodies
Research Use Only