CALHM1 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A7858-20, A7858-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear.
Synonyms: FAM26C; CALHM1
GeneID: 255022
Swiss-Prot: Q8IU99
Reactivity: Human, Rat
Calculated Molecular Weight: 38kDa
Observed Molecular Weight: 45kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 202-346 of human CALHM1 (NP_001001412.3).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200
Research Areas: Cancer, Endocrine Metabolism, Neuroscience, Calcium Signaling, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: SH-SY5Y, HepG2, U-87MG
Cellular Location: Cell Membrane, Endoplasmic Reticulum Membrane, Multi-pass Membrane Protein
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.