(KO Validated) DNMT3A Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-67769-60, E-AB-67769-120, E-AB-67769-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: DNMT3A
Target Synonym: DNMT3A; DNMT3A2; M.HsaIIIA; TBRS; DNMT3A
Research Areas: Cancer,Epigenetics and Nuclear Signaling
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9Y6K1
Background: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Concentration: 1 mg/mL
Immunogen: Recombinant fusion protein of human DNMT3A
Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 16kDa/81kDa/101kDa
Observed MW: 140kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only